having unprotected sex with a particularly skanky slut you just picked up on a night out, and praying you don't catch any STD's (sexually transmitted diseases) from her.
Dude 1: Man, I fucked a mega hot chick last night.
Dude 2: Woah! did you bag up?
Dude 1: Nah, didn't have any rubbers on me so I was running the STD gauntlet.
Dude 2: You should get yourself checked out dude, you might have AIDS.
by its-a me, mario! May 20, 2014
Get the running the STD gauntlet mug.