A cross between a Nut case and having your panties in a bunch. If your mental, or are insane, or get worked up over something SO stupid, your a panty case.
John Howard is a panty case.
"gee mang the FDA sure is getting worked up over that new drug, they are acting like real panty cases'
"gee mang the FDA sure is getting worked up over that new drug, they are acting like real panty cases'
by Hambo February 3, 2004
Get the panty case mug.