-When something is seen as really appealing and/or brings satisfaction to and idea or subject.

-Also can be a substitute for "you're mad" or "you're lying".
Teacher: " You got an A on your project Mark, keep up the good work."
Mark: "That's Big Nuke!"

John: "I have a girlfriend, she doesn't live in this country but she's definitely real."
Bob: "Thats Big Nuke bro, your girlfriend doesn't even exist!"
by Talexman2004 December 29, 2020
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