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When a normally polite, classy individual breaks out into ratchet and/or ghetto-like behavior upon hearing a ghetto song, such as twerking. Created in a Vine by QPark.
"Mike, I think you have Sudden Ratchet Syndrome."
"How can you say that?"
"The other week you were talking about the expense reports and then you heard "Don't Drop that Thun Thun" and started to twerk."
by CactusBactus October 31, 2013
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