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The syndrome common to female inhabitants of the state of Michigan.
Key characteristics include pronounced forehead and face that seems to be sucked in by the mouth giving a bitter look.
Some say that the patients look like relatives of hulk hogan.
Tom: Yo did you just see that chick, she must have just bit into a lemon or something cause she looked rediculous.
Lane: It wasn't a lemon, she just has a bad case of michigan down syndrome.
by alpa_chino August 22, 2008
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