(n.) The feeling of X-TREME pain and discomfort accompanied by the discoloration of the knuckles and pinky caused by playing Guitar Hero II for over 5 hours straight.
Teacher: d00d, wtf happened to your hand lolz? It'z all malformed and Y3110|/\|!!!11!!one!
Billy's Friend: He's got MAJOR GH Syndrome.
Billy: I was trying to play Freebird on expert for like, 10 hours. Oh god... I can't feel my pinky >_<!
Billy's Friend: He's got MAJOR GH Syndrome.
Billy: I was trying to play Freebird on expert for like, 10 hours. Oh god... I can't feel my pinky >_<!
by Garrett Funk June 4, 2007