Top definition
This is very similar to doing the Edward 40 hands game but instead four lokos are taped to the hands as opposed to 40s. Although in theory this seems like a great idea, do not be fooled, the next mornings hangover will be an awful experience.
- "Hey man you wanna take it up a notch and do Eduardo Manos Locos?"
- Hell yeah! Sounds like a great idea!"

...the next morning

- "I hate you so much."
- "My heart hurts."
by Robadoo November 12, 2010
Get the mug
Get a Eduardo Manos Locos mug for your Uncle Vivek.

Available Domains :D