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This is very similar to doing the Edward 40 hands game but instead four lokos are taped to the hands as opposed to 40s. Although in theory this seems like a great idea, do not be fooled, the next mornings hangover will be an awful experience.
- "Hey man you wanna take it up a notch and do Eduardo Manos Locos?"
- Hell yeah! Sounds like a great idea!"

...the next morning

- "I hate you so much."
- "My heart hurts."
by Robadoo November 12, 2010
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