seriquil Share definition Flag better than oxy will make you sleep like a sick little puppy for days. best consumed in 3s after the bar for a mild hibernation. we thought jesse was dead but he just ate a bunch of seriquil. hes a fuckin dirtbag seriquil by sikkkboii June 5, 2007 0 0 Get merch Get the seriquil mug. Buy Now — $32.95 See more merch