Tamper that box Share definition Flag 1 : To take the virginity of a female 2 : To penetrate the vagina. 3 : Anal rape 1 : Dude, I tampered Jenny's box 2 : Dude, tamper that box! 3 : Don't tamper me, bro Tamper that box by Insaniac82 December 2, 2007 0 0 Get merch Get the Tamper that box mug. Buy Now — $32.95 See more merch