cussleupagus 

any female who is a royal pain in the ass, a serious bitch, a derivative of cussle or cunt muscle, a phsyco slut

Murphy's girlfriend is a real cussleupagus!!

cussleupagus by Cusslemon June 30, 2008

Cuntleupagus 

Pronunciation: Sounds like the large woolly mammoth from Sesame Street (Mr. Snuffleupagus, Snuffy, Snuffaluffagus, etc) with the word cunt replacing the beginning.

Part of Speech: Adjective

Definition: Your fat bitch sister that is acting like a cunt.

Alternate Forms: Cuntaluffagus, Cunty, Ms. Cuntaluffagus

Boy, Brenda is being a real cuntleupagus tonight!

Cuntleupagus by Rapathy January 5, 2017