Bust Up or Bus'd up Share definition Flag (Verb) To haul ass or run away as if your life depended on it. "After I stabbed dat nigga I heard 5.0 comin so I Bus'd up. Bust Up or Bus'd up by Ronni August 30, 2004 0 0 Get merch Get the Bust Up or Bus'd up mug. Buy Now — $32.95 See more merch