Definitions by the big jo to the izzle

twizzle 

1. the act of making passionate sweet monkey love
2. to cuase extreme bodily harm to another person

"I twizzle that fly ass jive turkey last night and she howled like a bitch ass hoe"
"I twizzled the mo-fo when he tryed to hold a 45 to my head and wanted some green

twizzle by the big jo to the izzle July 22, 2003