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Definitions by chi-town bro

Common code word used by many Chicago street gang thugs meaning "Fuck The Opps" or "Fuck the Oppositions". The code word is generally used and aimed at the Chicago Police Department. Many of Chicago's rappers such as Chief Keef, Fredo Santana, and King Louie use this abbreviation in their songs.
Chief Keef: "FTO, O-BLOCK BANG BANG"
FTO by chi-town bro August 19, 2012