1 definition by Nick December
The sinking, sad feeling that one gets after finishing a really good, funny, or original anime. This feeling may also be extended to TV shows, music, books, and video games.
Anime nerd 1: Damn, dude! I just finished Death Note and i can't stop feeling dead inside!
Anime nerd 2: Sounds like a case of Post-Anime Depression to me!
Anime nerd 2: Sounds like a case of Post-Anime Depression to me!
by Nick December June 30, 2011