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Definitions by Mustache McGee

Skittle Herpes 

When a girl has herpes and makes a guy eat skittles out of her vag. He then eats a herpes cluster along with the skittle not realizing it. The girl's herpes is so bad it's in skittle sized clumps.
"Dude, don't even think about it. She has skittle herpes."
Skittle Herpes by Mustache McGee January 4, 2012