1 definition by Michaela Margaret

1. A fertile hybrid offspring of domestic cattle, Bos taurus, and the American Bison(a buffalo)
2. A piece of music that satisfying like beef(or rock) but low in fat like buffalo(or Devo)
1. "Dude, did you try that awesome beefalo burger? It fills you up but doesn't make you fat."
2. "That song Coming Up by Paul McCartney is so beefalo. I feel better for listening to it, not weighed down or empty."
by Michaela Margaret March 23, 2008
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