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Definitions by Kincaid Kjeedo

mano y mano 

"mano y mano" is Spanish for Hand to hand. Usually associated in engaging in throwing fisticuffs with two or more people, usually two.

Is layman's terms, a fight, but not usually followed closely to it's meaning. Often times, swords, or other weapons, not involved with guns or firearms, are associated with the term.
All right, Robin. Let's go at it. a fight to the death, you and me, Mano y mano, just you and me and my GUARDS!
mano y mano by Kincaid Kjeedo June 11, 2006