1 definition by Jfdadff

Top Definition
cis
Short for "cisgender" (opposite of "transgender"), used to describe someone whose gender identity matches their anatomical gender at birth.

Occasionally used derogatorily.
Mark: I heard that Stacy decided to start her transition.

David: Huh? Dude, Stacy is cis. You mean her sister.
by Jfdadff June 29, 2009

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