Top Definition
A typographical error caused by misplacing your typing fingers on the wrong keys on the keyboard.
1. I was on instant messenger talking to my friend and I got so mad at him that I tried to write back something really fast but all I wrote was a major zypo.

2. I wasn't paying attention to what I was writing and zypo'ed the whole paragraph.
by toast455 June 23, 2005
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