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1.
a HUGE monstrosity of a zit, often found on teenage faces. not to be used regarding peopel with major acne, ususlaly just on relatively normal faces that sometimes go PEUF! and develop huge ginormous pimples.
holy mother of time! that guy over there has a major zitzilla !!!
by the shoe hating taquito eater January 17, 2005
 
2.
A large and often fat person with so much acne they are unrecognizable as human.
Ben: Omg dude did you see that zit zilla?
Jeff: Yeah bro, you could pump oil from that thing.
by Bdub69 August 27, 2006