Top Definition
telling someone to fuck off in disbelief or annoyance.
cleo gets a wet willy from her friend:
Cleo: " vag off ! "

Izzy catches her girlfriend in bed with another women:
Izzy: You know what, vag off-I never wanna see you again.

Lola's friend gets her tickets to see the nirvana even though Kurt Cobain is dead:
Lola: " vag off ! "

by cleoizzylola August 23, 2008
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