Top Definition
A twenty-six ounce bottle of hard liquor.
I just bought a twenty-sixer of vodka.

You better pick up a twenty-sixer of tequila for the mix.

"I drank me a whole twenty-sixer!"
by CokoBWare January 21, 2004
A twenty six fluid ounce bottle of spirits, usually 80 proof (40% alcohol by volume). Also referred to as a fifth. Note that bottles referred to as twenty-sixers actually contain about 25.3 fluid ounces (750mL).
I usually drink about a twenty-sixer of vodka in a night.
by B_L December 07, 2006

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