Top Definition
A game payed in the inner city. All that is needed is yourself, a knife, and a tweeker (preferably walking through your back alley eyeing your huffy bike which may be missing a back wheel and chain). Stab the tweeker, then politely inform him that he is "it".
Last night i saw your dad and Rev. Gerald playing tweeker tag. meth
by gei27 June 30, 2010
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