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1.
v. conjugation of "Twitter" + "heckle", v. : to abuse a speaker or performer via Twitter followers in the audience whilst s/he is speaking/performing
Hey, @bobsomeone, let's tweckle the keynote guy on stage and get all our friends to walk out of his Powerpoint right NOW!
by JonnyBigByte October 06, 2009
 
2.
a noun used in place of physically or mentally handicapped.
"Look at the tweckle in the wheel chair."
by Miagi April 09, 2008