Drunk and high...straight up. This usually occurs when one smokes a blunt directly after consuming a large amount of alcohol in a small amount of time.
Yo, yo, yo, yo......yo. I can't go to 7-11 yet because I am to' up from the FLO' UP. Goddamn, nigga, don't touch me.
by Douglas from Burnie June 28, 2007

9 Words Related to to' up from the flo' up

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