When you stroke your thumb on your handheld touch device but it doesn't register because you are wearing gloves.
Why isn't my iPhone working! I can't believe I spent all this money on this piece of junk! Screw you Apple!

Dude you're thumb blocked. Take off your gloves dumba$$.
by Kt-Mack February 13, 2010
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Simlilar to cockblocked, this is when someone else prevents you from something benificial in or around a videogame.
My friend's workplace thumb blocked me when he promised to give me a ride to pick up Resident Evil: DS and they called him in the day of release.

That noob just thumb blocked my windstorm by winning a roll, he doesn't even need it!

I got thumb blocked when Halo 2 came out and the banks closed early.
by Vincent Nasco February 6, 2006
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