take up with 

1930's expression for "fuck" (vulgar) or "see" (polite). You hear this expression in old movies, or recent movies (like Get Low) which is about the 1930's.

In the old days we'd say, "When did you take up with Sallie Mae?-- after all she's a married woman." Today we would say, "When did you start seeing Sallie Mae?" Or, "When did you start fucking Sallie Mae?"

take up with by Gabinox October 26, 2011

Take it up with my butt because that's the only one that gives a crap 

A phrase you can inject in a conversation after someone begins to complain or go on about something that you are not interested in.

Take it up with my butt because that's the only one that gives a crap.

Take it up with my butt because that's the only one that gives a crap by General America December 19, 2010