an Ass-hole, a dick. A man or woman who is getting on your nerves and they are being extremely aggravating and annoying. A jerk who is punking you around. An son of a bitch who likes to hurt others with offensive laguage. If you have ever worked in retail, this means the customer who went out of their way to make their transaction impossible to complete (asking for a manager, exct.) A cheap-skate.
"This son of a bitch is a syste-meizer."
"SYSTE-MEIZER!" <--- could be said to their face without them knowing what you are talking about.
"stop being such a syste-meizer."