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Refering to when a car is producing enough exhaust to spin the the turbochargers turbine fast enough to create noticeable boost.
My GT30R turbo spool up at about 4,500 RPM.
by MikeJones818 June 10, 2006
Air Traffic Control term. To spool up is to mentally prepare for busy traffic.
Hey Doc, better spool up, here comes the arrival rush.

I'd better spool up, looks like I won't be getting any help from the next sector.
by Al-Saladin June 21, 2009