A female with whom you share parents. Depending on the birth order she can be 1. your friend or 2. the BIGGEST BITCH EVER.
1. My sister is going to take me to see Iron Man 2.
2. My fucking sister just stole my wallet.
by 2buckchuck July 29, 2010
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Short for "The Sisters of Perpetual Indulgence." The Sisters are a world-wide order of 21st Century, queer nuns who serve the LGBTQ and other marginalized communities. The members of the all-volunteer organization, after an extensive training process, take lifelong vows in service of the community. Namely, to promulgate universal joy, expiate stigmatic guilt, and the pursuit of spiritual enlightenment. They accomplish their vows in countless ways, but the most common are through progressive, social activism, street theater, and non-denominational ministry without judgement. They also raise thousands, upon thousands of dollars each year which they grant out to those in need. www.thesisters.org
Hey, The Sisters are hosting Easter In The Park in GG Park again this year. The theme is "WTF Mary? Hunky Jesus, Take The Wheel." You wanna go with me? I bet you'd win the Hunky Jesus contest!
by Sister Dharma Gettin' February 22, 2015
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Noun//A sister is created by your parents therefore making them your sister. They can be one of two things 1. A best friend who you share everything with 2. A living nightmare that gets you into trouble and is gonna stick with you until you move out. Its usually the second option. If you have a sister...good luck. You’ll need it.
1. My sister and I went shopping and she bought me ice cream!
2. My sister broke the dining room window while practicing baseball, and she blamed it on me.
by LeahPea26 July 14, 2019
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Someone you have to live with until you or they move out also they are really annoying
Her: my sister is so annoying I can't wait till she moves out
by Maddy6666 July 3, 2020
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verb (to sisterize):

When a boy definitely and abruptly truncate any potential intercourse with a girl. Harder than friend zone.
I'can only look at you as a sister. I have to sisterize you.
by Castroman May 17, 2016
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A demonic creature that will always try to ruin your life and will try to blame everything on you to get you in trouble.
My sister tried to steal my wallet.
by Coolbro121121 December 17, 2016
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The rudest person to ever exist, they are rude and ruthless. They always wanna boss you around, but you still love them.
Who the meanest person you know?

My sister obviously.
by Deextrann February 9, 2020
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