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2.
A lower functioning state that a person goes into when they are sick. The state of being ill and feeling awful. It's the opposite of being in the zone. Coughing, sneezing, headache, running nose, stuffiness, or just generally feeling like grim death can constitute being in Sick Mode. Family, friends, and co-workers are expected to be understanding and give the person in Sick Mode a break because at some point everybody has been in Sick Mode.
John: I'm can't come to work today. I'm in Sick Mode.
Boss: Alright, feel better.

Kate: Honey, can you take care of the kids today. I'm in Sick Mode.
Jack: Okay. Just stay in bed and rest up. I've got this.
by MadMan50 January 28, 2011
 
1.
sickmode is a take on the word sick which can mean good cool nang. it originated in the midlands mainly nottingham, derby,lincoln, birmingham.. used a a positive way to express how a man feel about something.

Also, a way of saying that someone/a team/something performed well.
Ahh Blud Dem Lyric is Sickmode.

Man U we're shit first half. but dey went into sickmode in the 2nd half. get me.
by DUSTY P MC June 19, 2006