Top Definition
One of the greatest and offensive websites with strictly cartoon animations more often than not including sexual content.

The new sick animation cartoon is hilarious, I almost pissed my pants!
by Edwin Gaffney February 01, 2006
A website with some rather, um, interesting comedy cartoons & comics.
Man, did you see that shit on SickAnimation?
Fuck yeah man I got teh 5-0 fo' ma homiez lulz
by Tom 'Lanky' B. February 15, 2008
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