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1.
Someone who prevents you or a friend from taking a shot of liquor.

Cock blocking with alcohol instead of pussy.
"I bought Sam a shot of tequilla but he couldn't drink it cuz his girl was trippin and being a shot blocker."
by Juice 575 May 16, 2007
 
2.
A person who blocks someone from throwing a pwadded up piece of trash into a waste basket as if it were a basketball.
He shoots and he..." "Rejected!" "Damn you Greg! You f*cking shot blocker!
by WouldBeAmazingShot August 15, 2010