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Informal nickname for a really fun, cool, authentic, funny, and laid back sister and/or closest friend.
Dude, me and my closest sissel were totally talking about that the other day!
Related Words

Swissels 

A retarded piece of shit bar located in Fort Gratiot, MI. The owner is a fat cunt but the bartenders are cute.
Have you gone to Swissels lately?
No, everytime I go by Kim is there.
Swissels by (_l_) January 22, 2011

scisserb 

pass me the scisserbs.
you slippin on the scisserb
scisserb by notmyrealnameithink November 22, 2013
Sisseli - A fun, unique and loving girl who's very pretty but doesn't know it. She may often be jealous of those close to her, but she's always there when you need her. Sisseli has a very caring nature, and does not give up on her closest friends. You don't want to mess with her or her friends, because even if she's really sweet, she's also really sour.
Izzy: Hey, there's Sisseli!

Jean: Let's go talk to her!
sisseli by iiAmSpooky June 11, 2017

Schissel 

Josephine, you fat pig! You ate the entire d**n schissel of broc and beans...idiot!
Schissel by Jaburkburk January 11, 2012
Sissel is a human, but barely. Sissels tend to be mean spirited and hypocritical.

If you ever meet a Sissel, you should run as fast as possible in the other direction.

Watch out for Sissel.
Ugh, that girl is such a bitch!

Bitch is an understatement, that's a Sissel!
Sissel by ChickenNuggetNoodle January 14, 2019