Run me your shit is another way of saying give me everything you have Used in slang mainly in England in places like Birmingham Essex or Milton Keynes normally in dodgy back streets when you are getting mugged on the street in England by someone.
Roadman: RUN ME YOUR SHIT RIGHT NOW FAM OR ILL SHANK YOU BRUV!
You: please don't kill me I have a wife and kids.
Roadman: SHUT THE FUCK UP!
by Pigeon Squad March 2, 2022
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Basically when two people are having a confrontation and one of them wants to fight, they will say "run me my shits". It's a long way around just saying "fight me right now".
Bob fucks Jim's girlfriend*
Bob: Bro I didn't mean to fuck her

Jim: Run me my shits
They proceed to fight*
by The passion of the christ February 5, 2017
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Its how you describe to someone that you are absolutely flat on your back from influenza or a cold and unable to even stand up to do the most menial tasks in life like going to the bathroom or eating
Bill: I heard that you have the flu, how are you feeling?

Tom: Well Bill , I happen to feel like Run Over Rubber Dog Shit, its absolutely terrible
by Freeze_Riggs July 3, 2016
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