Top Definition
When somebody sees you sneeze, blow your nose, scratch yourself, or touch something dirty just prior to shaking your hand, and you are forced to use your left hand instead of your right to avoid further embarrassment and grossing the person out.
Dialogue involving a reverse handshake:

1: Hi, 2! (reaches to shake 2's right hand)

2: (quickly sneezes, grabs a tissue to quickly clean his right hand and shakes using his left hand.) Sorry, Hi!
by redblade77 January 11, 2009

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