When one is truly dealt a bad hand by nature. Used to describe one who is so horribly hopeless and worse off than anyone else, they have truly been pwned by life.
"Man, Travis' dad just got diagnosed with cancer."
"Right after that black kid stole his bike, and fucked his girl?"
"Yeah dude."
"Oh man, pwned by life."
by DickDanger November 12, 2007
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