Top Definition
The most derogatory word for a woman. Worse than calling her a cunt, whore, slut, etc.

a "pustrampuss" is a pussy that has been fucked so many times, the lips hang down like chewed up bubble gum. You will see this often in porn.

Pustrampuss is the combination of the words "pastrami" and "pussy"
Dude, that girl is so beat. Her pussy was like chewed up bubble gum. Dirty pustrampuss whore!
by Nick Cofphee October 16, 2007

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