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Slang used to described a woman who's into "bad boy" types and is in and out of relationships with men who have been in prison or had trouble with the law.

The "flea" part describes how she hops from ex-con to thug.
Rick: I thought Lucy was dating regular guys?
Steve: Are you kiddin'? After she quit school and started doing crack, she turned into a god damn prison flea.
by Kwanzaa Shrub January 10, 2012