It is a (semi-funny) response, seen a lot on social media like reddit, for example for someone with no chance of surviving a gaming battle due to enemy superior force , originally from 2014 first-person shooter Call of Duty: Advanced Warfare. Quoting know your meme :

"Press F (X) to Pay Respects is an action prompt featured in a quick time event from the 2014 first-person shooter Call of Duty: Advanced Warfare. Upon the release of the game in November 2014, many players of the game mocked the funeral cutscene for its forced element of interactivity that seemed out-of-place at a memorial service."

F
"Press F to pay respect"
"Press F (X) to pay respect"

Press F to pay respect by MoFazul September 21, 2017

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error: no keyboard detected. press F5 to continue

Well? What are you waiting for? Do it!

Error: no keyboard detected. Press F5 to continue.

error: no keyboard detected. press F5 to continue by I ain't tellin you NoTHIN'! July 20, 2006

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press f to pay respect

When someone has taken a BIG L or has been oofed so hard that they may feel emotional pain

This term can be abbreviated to the letter F

Man : "i got regected last week"
Everyone : "F"

Press F to pay respect is a general term or responce after someone feeling emotional or physical pain

press f to pay respect by Yognaught_001 July 25, 2019

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