Top Definition
Poke Dope, is slang terminology for shooting up, or slamming drugs into the vein, via a needle or (Rig), it is a general definition for all drugs that are injected into the vein through a needle, and doesn't pertain to any particular one.
"I was really into poke dope back in the day."

"John is a real fiend for that poke dope."
by TylerLu December 03, 2007
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