Broken down, "pissed-up" means inebriated or drunk. A "slapper" is, well, a slut. Or, a woman of loose morals. So, a "pissed up slapper" is also known as a drunken trollop or whore.
"Lets go to the bar tonight and pick up a couple of pissed up slappers." "Check that pissed up slapper going down on Mark in the corner." "It's a sure thing cause she's a pissed up slapper."
by junkietown May 25, 2009