its really an abbreviation...but it stands for "pent up sexual frustration"...
I've had a lot of "p.u.s.f." lately it, I hope Ben comes over tonight.
by supergirlmiyea September 25, 2006
1 more definition
Pent Up Sexual Frustration. PUSF can be light, or life threatening.
This PUSF is ruining my fucking life!
by essjay90 October 05, 2010