its really an abbreviation...but it stands for "pent up sexual frustration"...
I've had a lot of "p.u.s.f." lately it, I hope Ben comes over tonight.
by supergirlmiyea September 25, 2006
Pent Up Sexual Frustration. PUSF can be light, or life threatening.
This PUSF is ruining my fucking life!
by essjay90 October 05, 2010