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1.
A term used for a girl who thinks she is nice and that her enemy is not, but in reality neither is nice. Comes from the words "opposite" and "bitch".
Becky: Tori is so mean! I'm so nice, why does she pick on me? Stupid slut.

Lola: Just try to get along.
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Tori: Becky is so mean! I'm so nice, why does she pick on me? Dumb bitch.
Lola: Just try to get along.
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Amber: Wow. They both think they're the good one.
Lola: Yeah, but both are the bad one. They're oppobitches.
by AwesomazingWordInventor September 16, 2013
 
2.
The exact opposite of a bitch

Nice, kind, helping.
Max: I heard Kelsea voluntaries at the homeless shelter, and collects charity.

Joey: Yeah, shes a huge oppo-bitch!
by Eshady08m June 08, 2009