a bag of heroin and coke together.
i wanted to do a speedball so i told my connect i need a "one and one" bag.
by fresh stallion April 12, 2010
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san francisco bay area slang for a combination of cocaine and heroin, aka a "speedball". a hit of tar heroin and powder cocaine sold together on the street for $10 to $20.
if youre in a san francisco neighborhood such as the mission, and you hear a guy calling out "one on oners, one on oners", hes not challenging you to a game of basketball.
by beau "oma" taylor March 14, 2010
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In paintball, when a player on one team and a player on the other team mark (shoot) each other at the same time, therfore resulting in a "one for one", one player is eliminated with another player from the opposing team.
Larry ran to bunker Steve and Steve shot Larry as Larry shot Steve. The ref couldn't tell who shot first, so he called a one for one.
by Kyle Taylor May 9, 2007
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1. When you go from dating someone to being in an exclusive relationship.
2. Becoming someone's boyfriend or girlfriend.
Friend 1: Dude, when are you guys gonna go one on one?
Friend 2: I'm not ready for a relationship yet.

Friend 1: I thought you were going one on one with her.
Friend 2: Naw, man. I don't want to give up the other pussy.
by Juppy George January 16, 2009
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The phrase that people say that suck at everything but is the best in their little village where they live when they lose in a team-based. Normally followed by a really bad yo momma joke.
John: God dude, you really suck at everything.
Gaylord: what, you wanna go one on one, because I'm in your mom's bed.
John: (pause) Wow... really?
by JoshRoxxx July 30, 2008
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I am the one the one the one. Try to unscramble this message. I W I L L N O T L I V E T H A T L O N G P L E A S E H E L P
by GokuAnanta_SSJB May 19, 2020
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