Used to describe a person when he/she is doing things in ways that are extremely out of the ordinary. This can have a negative or positive connotation, depending on context, such as describing a person who is mind-blowingly creative, or perhaps just out of control or not acting normal. In the positive light, "On some other shit" is often interchangeable with the slightly older phrase on another level. It also doubles (and originates) as a drug reference, describing a situation where a person is taking more intense drugs than usual.
Leon: "Yo, Nicki Minaj's verse on Kanye's Monster joint was on some other shit!"
Charlie: "Yeah man, she killed it!"

Leon: "Yo, dawg, what was up with you last night at that party? You was mad sloppy..."
Charlie: "Yeah, man I was on some other shit... Natalie broke up with me."

Leon: "Yo did you seeee Frankie last night?! Boy was high as a kite!"
Charlie: "Psh yeah, he must've been on some other shit or somethin..."
by AndWeDRay August 22, 2011
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When someone is behaving in such a way that is not normal human behavior, or typical of any known man made drug.
by yesitsmeagain September 11, 2008
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Doing, or acting crazy, Krunk, unapproiate, inapproiate, and or out of the regular aspect of things
yo bitch I was on some other shit at that Krunk ass party last night.
by fuckyocouch3369 April 29, 2008
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1. being on drugs people are not customed to.

2. acting differently than the way people know you to. (being upset, or too hyper)
1. "she was on some other shit last night, i dont even know what that drug was called"

2. a: "why you on some other shit?"
b: "how im on other shit?"
a: "you all upset, for no reason"
by pro121c June 20, 2009
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