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Newfoundland slang for being annoyed, pestered, irritated. Another way of saying "that gets on my nerves". Another way of saying "my patience is gone". It is also sometimes used as a response - instead of oh my gosh, no way, get outta here.
Conner: The cost of gasoline just went up again!
Betsy: Oh me nerves is gone!
by The Gewfie Newfie January 19, 2011