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One's nieces and nephews.
I can't go out tonight, I'm babysitting my niephews.

I have 8 niephews; 3 nieces and 5 nephews.
niephew by unkleB September 16, 2008
Related Words
noun: A niece or a nephew.
adjective: of or pertaining to a niece or nephew.

plural: niephews

http://www.askoxford.com/asktheexperts/faq/aboutwords/siblings?view=get

"I have four niephews: three nephews and a niece."

"Three of my niephews are my first sister's children (two sons and a daughter), and my fourth niephew is my second sister's child (a son)."
niephew by imperatrix March 27, 2009
When you don't know if you'll be having a niece or nephew.
I can't wait to figure out what my niephew is!
Niephew by Kjtheblogger June 3, 2017
Gender neutral equivalent of niece/nephew.
My niephew Jade identifies as nonbinary now...
Niephew by T17745 May 1, 2022
Noun: (nee-few) The gender neutral form of niece and nephew
I have 7 niephews.

With my 8 nieces and 6 nephews I have a total of 14 niephews.
Niephew by Zip.Kelvin January 8, 2016

niecefews 

Short for neices and nephews.
My Aunt Nancy calls my brother, my sister, and me her niecefews!
niecefews by vwallac October 9, 2006