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1.
The grime that collects on gaming mice and mechanical keyboards after countless hours of being handled by nerds.
I have to clean that nerd grime off my mouse before I go to the LAN.
by zedd11 January 09, 2012
 
2.
The collection of dead skin cells in the cracks of mice due to advanced levels of gaming.
Dude, your mouse is full of nerd grime.
by DaveIsANerd January 19, 2012