A Nachos Twatgrande is a description of a girl with a particularly nasty cooch. Characterized by a crusty, flaky shell, and something resembling cheese, as well as green and white pasty substances around the perimeter. If you see tomato chunks, go directly to the free clinic, do not pass go.
That fat girl I picked up in Fairfax last night was disgusting. She had a giant hairy Nachos Twatgrande. I damn near threw up on my churro.
by Captian Colostomy May 08, 2006